On the night of April 22, the Israeli Defense Forces continued their operations in the Gaza Strip. Only Gazan sources reported on the military situation there overnight.

In northern Gaza, the IAF targeted a house in the Zeitoun neighborhood of Gaza City that belongs to the Iyad clan.

In central Gaza, the Israeli Navy shelled targets on the western outskirts of Az-Zawayda and Deir al-Balah. An IDF drone struck a target in Bureij. IDF artillery shelled Nuseirat, with reports of damage to Al-Awda Hospital. IDF artillery also targeted areas north of Nuseirat in Al-Mughraqa and Al-Zahra, as well as east of Al-Maghazi. The IAF conducted strikes on targets in the al-Bureij refugee camp.

In southern Gaza, the IDF struck a target southeast of Khan Yunis, and the IAF conducted strikes on targets in Khan Yunis itself.

As of now, the IDF has commented on the military operations in Gaza on April 22.